Trilostane yog ib qho muaj zog inhibitor ntawm 3 -hydroxysteroid dehydrogenase, dav siv hauv cov kws kho tsiaj thiab tib neeg cov tshuaj. Nws yog feem ntau qhia rau kev kho mob ntawm Cushing's syndrome, thawj hyperaldosteronism, thiab ntau yam adrenal- cuam tshuam txog cov tshuaj hormonal. Vim nws cov txiaj ntsig zoo hauv kev tswj hwm ntau tshaj corticosteroid ntau lawm, Trilostane feem ntau pom zoo rau dev, miv, thiab nees nrog hyperadrenocorticism (HAC). Nws kuj tseem yuav tau txais txiaj ntsig zoo rau qee yam tsiaj uas raug mob los ntawm alopecia-txoj kev mob xws li Alopecia X hauv Pomeranians thiab cov neeg laus- pib alopecia hauv Alaskan Malamutes.
Khoom Paub meej
|
Parameter
|
Specification
|
|---|---|
| Molecular Formula | C₂₀H₂₇NO₃ |
| Molar Mass | 329,43 g / mol |
| Qhov ntom | 1.1213 (kwv yees) |
| Melting Point | 264 degree |
| Boiling Point | 467.02℃(kwv yees) |
| Kev sib hloov tshwj xeeb ( ) | D25 +137.4℃(c=1, pyridine) |
| Flash Point | 254,8 degree |
| Solubility | DMSO Ntau dua lossis sib npaug ntawm 17 mg / mL |
| Vapor Siab | 5.39E-12 mmHg ntawm 25 degree |
| pKa | 8.57 ± 0.70 (kwv yees) |
| Refractive Index | 1.5614 (kwv yees) |
| Qhov tshwm sim | Hmoov |
| Xim | Dawb mus yuav luag dawb |
| Cia | Khaws rau hauv ib lub thawv kaw ntom ntom, airtight ntim |
Daim ntawv thov
✔ Kev Kho Mob Cushing's Syndrome
Trilostane feem ntau yog siv los kho pituitary - thiab adrenal -dependent hyperadrenocorticism (HAC) hauv dev, miv, thiab nees. Nws inhibits corticosteroid synthesis, uas pab txo cov tsos mob xws li nqhis dej ntau dhau, tso zis ntau ntxiv, plaub hau poob, thiab qaug zog.
✔ Kev kho mob ntawm Primary Hyperaldosteronism
Qhov no yog ib qho mob tshwm sim los ntawm kev tsim cov aldosterone siab. Trilostane txhawb nqa electrolyte homeostasis thiab txo cov tsos mob ntsig txog kev kho mob.
✔ Txhawb Kev Kho Mob Alopecia Disorders
Trilostane txoj kev kho tau txais txiaj ntsig tshwj xeeb, xws li:
- Pomeranians nrog Alopecia X.
- Alaskan Malamutes nrog cov neeg laus- pib Alopecia
Cov tshuaj yuav pab kom rov qab hormonal tshuav nyiaj li cas, uas yog txuam nrog cov plaub hau follicle noj qab haus huv.
✔ Adjunctive Therapy for Post -mob qog noj ntshav mis
Trilostane tuaj yeem siv los kho mob qog noj ntshav ntawm lub mis hauv cov poj niam postmenopausal los ntawm kev txo qis cov tshuaj hormones adrenal, uas ua rau cov qog nqaij hlav.
Yuav ua li cas Trilostane ua haujlwm
corticosteroids yog qhov tseem ceeb rau:
- Cov metabolism hauv lipids, proteins, thiab carbohydrates
- Kev ntxhov siab
- Kev tswj cov ntsev thiab dej sib npaug.
- Cov zis ntau dhau ua rau muaj teeb meem kev noj qab haus huv loj.
Trilostane inhibits kev tsim cov tshuaj corticosteroids, yog li txhim kho cov tshuaj hormones thiab tswj cov tsos mob zoo.
Ntim thiab xa khoom xaiv
Peb muab kev daws teeb meem kev xa khoom yooj yim thiab txhim khu kev qha:
- Kev Pabcuam Express: FedEx, DHL
- Kev thauj mus los hauv huab cua muaj kev xaiv ceev thiab ruaj ntseg rau kev txiav txim loj.
Muag & Kev Pabcuam
Xiamen Keeb Kwm Biotech tau cog lus tias yuav nthuav dav nws txoj kev mus thoob ntiaj teb thiab tsim kev sib koom tes ntev -. Peb lub zog muaj xws li:
- Premium khoom zoo.
- Muaj zog technical support.
- Kev muag khoom thiab tom qab- kev muag khoom.
Peb cov khoom raug xa tawm thoob plaws ntiaj teb, suav nrog Tebchaws Europe, North America, South America, Middle East, thiab Asia, thiab peb tau txais cov lus pom zoo los ntawm peb cov neeg siv khoom.
Cim npe nrov: Tuam Tshoj Trilostane CAS 13647-35-3 manufacturers, lwm tus neeg, Hoobkas
