Tib neeg Prostaglandins
Koj tus kws tshaj lij Human Prostaglandins Supplier
Xiamen Keeb Kwm Biotech Co., Ltd., muaj ntawv pov thawj 'State Hi-tech Enterprise,' tshwj xeeb hauv kev koom ua ke ntawm R&D, kev tsim khoom, thiab kev muag khoom ntawm tib neeg thiab tsiaj txhu APIs thiab intermediates. Lub tuam txhab cov khoom lag luam suav nrog cov tshuaj hormones, proteins thiab peptides, prostaglandins, me me molecule compounds, thiab lwm yam APIs. Cov khoom lag luam no tau siv dav hauv kev tsim tawm, endocrinology, thiab gynecology, catering rau tib neeg thiab kws kho tsiaj.
Customized Services
Xiamen Keeb Kwm muab cov kev daws teeb meem rau cov khoom tsim thiab R & D cov kev pabcuam rau cov khoom tshiab, ua raws li cov neeg xav tau tshwj xeeb.
Extensive Expertise nyob rau hauv Pharmaceutical Production
Peb pab neeg muaj kev paub dhau los hauv kev tsim tshuaj thiab tau nruab nrog cov kev txawj ntse uas yuav tsum tau ua kom tau raws li cov neeg siv khoom xav tau ntau yam.
Kev Tswj Xyuas Kev Tswj Xyuas Zoo
Peb siv cov txheej txheem tswj hwm nruj ntawm txhua theem ntawm kev tsim khoom, los ntawm kev tshuaj xyuas cov khoom siv raw mus rau kev saib xyuas ib puag ncig, ua kom muaj kev ua raws li cov qauv kev lag luam siab tshaj plaws.
Advanced Manufacturing Infrastructure
Peb qhov chaw tsim khoom nthuav dav tag nrho thaj tsam ntawm 2,523 square metres, suav nrog Chav D chav huv ntawm 365 square meters. Lub chaw tsim khoom yog tsim thiab tsim ua raws li GMP cov cai, kom ntseeg tau tias cov khoom siv tau zoo.
Tib neeg Prostaglandins
Prostaglandins yog bioactive lipid compounds uas ua lub luag haujlwm tseem ceeb hauv ntau yam txheej txheem physiological hauv tib neeg lub cev. Lawv koom nrog hauv kev tswj kev mob, ntshav khiav, kev tsim cov tshuaj hormones, thiab lwm yam kev ua haujlwm lom neeg. Qee cov prostaglandins kuj tseem siv los ua cov khoom xyaw tshuaj nquag (APIs) hauv kev kho mob.
Rau pawg no, Keeb Kwm Biotech muaj cov khoom xws li Latanoprost, (-)-Corey Lactone Diol, Travoprost, thiab lwm yam.
Latanoprost yog ib qho prostaglandin analog feem ntau siv hauv ophthalmology kom txo qis intraocular siab hauv cov neeg mob uas qhib -angle glaucoma lossis ocular hypertension. Nws yog nyob rau hauv chav kawm ntawm cov tshuaj hu ua prostaglandin F2alpha analogs. Latanoprost ua haujlwm los ntawm kev ua kom cov dej ntws tawm ntawm lub qhov muag, uas pab txo qis intraocular siab. Qhov no tuaj yeem pab tiv thaiv kev puas tsuaj rau lub paj hlwb thiab khaws cia tsis pom kev. Latanoprost muaj nyob rau hauv ntau hom xws li tshuaj loog, tshuaj kho qhov muag, thiab tshuaj kho qhov muag. Nws feem ntau yog muab tshuaj ua ib zaug - noj tshuaj txhua hnub rau ntev - siv sijhawm ntev.
(-)-Corey Lactone Diol, tseem hu ua Latanoprost acid, yog cov nquag metabolite ntawm Latanoprost. Tom qab tshuaj pleev ib ce ntawm Latanoprost, nws yog hydrolyzed rau (-)-Corey Lactone Diol nyob rau hauv lub qhov muag. Cov metabolite no khaws cov tshuaj pharmacological ntawm Latanoprost thiab pab txhawb rau nws cov teebmeem kev kho mob hauv kev txo qis intraocular siab.
Travoprost yog lwm cov tshuaj prostaglandin analog uas siv los kho qhov qhib -angle glaucoma thiab ocular hypertension. Nws yog ib tug hluavtaws derivative ntawm prostaglandin F2alpha thiab sib koom ib tug zoo sib xws mechanism ntawm kev txiav txim nrog Latanoprost. Zoo li Latanoprost, Travoprost ua rau kom cov dej ntws tawm ntawm lub qhov muag, ua rau kom txo qis hauv cov ntshav siab. Nws muaj nyob rau hauv cov tshuaj ophthalmic rau cov tshuaj pleev ib ce thiab kuj tau sau ib zaug ib hnub.
Ob leeg Latanoprost thiab Travoprost tau ua pov thawj tias muaj txiaj ntsig zoo hauv kev tswj cov glaucoma thiab ocular hypertension los ntawm kev txo qis intraocular siab. Txawm li cas los xij, kev xaiv tshuaj yuav txawv raws li tus neeg mob tus yam ntxwv, suav nrog lawv cov mob tshwj xeeb, cov lus teb rau kev kho mob, thiab cov kev mob tshwm sim. Nws yog ib qho tseem ceeb rau cov neeg mob ua raws li cov lus qhia los ntawm lawv cov kws kho mob thiab siv cov tshuaj raws li qhia.
Hauv kev xaus, prostaglandins xws li Latanoprost thiab Travoprost yog cov txiaj ntsig APIs siv rau kev kho mob glaucoma thiab ocular hypertension. Cov tshuaj no ua tau zoo txo qhov siab ntawm lub paj hlwb thiab pab tswj kev pom.
Zoo siab txais tos nug txog tib neeg cov khoom API, thov ntseeg tias Keeb Kwm Biotech yuav muab rau koj nrog siab - cov khoom zoo, tus nqi nyiam, thiab cov kev pabcuam siab.
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Molecular Formula |
C22H36O5 |
C26H35F3O6 |
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Molar Mass |
380.52 |
500.55 |
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Qhov ntom |
1.118 |
1.245 ± 0.06 g / cm3 (Tshaj tawm) |
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Melting Point |
97-100 degree |
/ |
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Boling Point |
550.6 ± 50.0℃(Predicted) |
584.8 ± 50.0℃(Predicted) |
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Flash Point |
300.9 degree |
17 degree |
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Solubility |
DMF: Soluble |
DMF: Soluble |
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Qhov tshwm sim |
Crystalline |
Ethanol daws |
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PKa |
4.78 ± 0.10 (Kev kwv yees) |
13.43 ± 0.20 (Kev kwv yees) |
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Kev cia khoom |
-20 degree |
Muab ntim rau hauv qhuav, Khaws rau hauv lub freezer, Hauv qab -20 degree |
Hom Human Prostaglandins
Tib neeg prostaglandins tsim los ntawm peb lub tuam txhab feem ntau suav nrog cov hauv qab no:
(+)-Corey Lactone Diol
Corey lactone diol yog ib qho tseem ceeb nruab nrab compound siv nyob rau hauv lub synthesis ntawm ntau yam tshuaj. Cov tshuaj no yog siv los tsim tshuaj tua kab mob, tshuaj tiv thaiv - mob, thiab tshuaj tiv thaiv - mob qog noj ntshav. Nws muaj cov qauv tshuaj tshwj xeeb uas ua rau nws yooj yim los hloov kho thiab zoo - kho nws cov khoom kom tau raws li cov kev cai kho mob tshwj xeeb.
Corey Lactone Benzoate
Corey Lactone Benzoate, tseem hu ua CLB, yog ntau yam thiab muaj txiaj ntsig zoo siv dav hauv ntau qhov kev lag luam vim nws cov khoom siv tshuaj lom neeg tshwj xeeb. Qhov no tsis muaj xim lossis daj daj crystalline khoom yog soluble hauv ntau cov kuab tshuaj organic thiab muaj cov ntxhiab tsw txawv, ua rau nws siv tau rau ntau yam kev siv.
Latanoprost
Latanoprost yog ib qho tshuaj zoo siv los kho tus mob glaucoma thiab txo qis intraocular siab, pab tiv thaiv kom tsis pom kev ntxiv thiab txhim kho qhov muag tag nrho.
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Biological System |
Physiological nyhuv |
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digestive system |
Txo cov kua qaub secretion; Nce ntawm mucous secretion |
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Longitudinal du nqaij contraction; Circulatory smooth nqaij contraction |
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Ua pa system |
Bronchodilator |
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Bronchoconstriction |
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Cardiovascular system |
Arterial vasodilation |
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Inhibition ntawm platelet adhesion thiab leukocyte aggregation |
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Lub raum system |
Medullary ntshav khiav, Siab diuresis |
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Renin tso |
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Natriuresis, diuresis |
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Kev tiv thaiv kab mob |
Inhibition ntawm proliferation thiab ua kom T thiab B lymphocytes |
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Central paj hlwb |
Kev mob |
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Induction ntawm pw tsaug zog |
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Poj niam ua me nyuam system |
Ovulation, Implantation, Endometrial contraction, thiab Synergism nrog oxytocin |
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Txiv neej lub cev xeeb tub |
Fertility |
Human Prostaglandins Analysis Methods
Mass Spectrometry (MS):
Mass spectrometry (MS) yog ib txoj kev tshuaj ntsuam ntau yam uas ua rau cov kws tshawb fawb los txiav txim siab qhov loj ntawm - rau - tus nqi piv ntawm cov molecules, muab kev nkag siab tseem ceeb rau lawv cov qauv molecular. Hauv thaj tsam ntawm kev tshuaj xyuas prostaglandin, MS muaj ntau qhov zoo sib xws:
● High Sensitivity:MS nthuav tawm qhov zoo tshaj plaws rhiab heev, ua rau nws muaj peev xwm kuaj pom cov tshuaj prostaglandins txawm tias tam sim no nyob rau hauv qis concentrations nyob rau hauv complex biological kuaj.
● Kev txheeb xyuas:MS excels ntawm kev txheeb xyuas prostaglandin molecules raws li lawv qhov tshwj xeeb huab hwm coj spectra, uas yog tshwj xeeb rau txhua hom prostaglandin. Qhov kev muaj peev xwm no ua rau kev txiav txim siab raug ntawm cov subtypes ntawm prostaglandins tam sim no hauv ib qho piv txwv.
● Quantification:MS kuj tseem tuaj yeem ntsuas cov prostaglandins los ntawm kev sib piv cov kev siv ntawm lawv cov peaks loj rau cov qauv sab hauv. Qhov loj me me no yog qhov tseem ceeb rau kev nkag siab txog qib ntawm prostaglandins hauv cov kab mob lom.
Liquid Chromatography-Mass Spectrometry (LC-MS):
Cov kua chromatography-mass spectrometry ua ke cov peev xwm sib cais ntawm cov kua chromatography nrog lub zog analytical ntawm huab hwm coj spectrometry. Hauv kev tshuaj xyuas prostaglandin, LC-MS muaj cov txiaj ntsig hauv qab no:
● Kev sib cais:LC cais prostaglandins los ntawm lwm cov tebchaw hauv ib qho qauv raws li lawv cov khoom siv tshuaj, xws li polarity thiab hydrophobicity. Qhov kev sib cais no txo qis kev cuam tshuam thiab txhim kho qhov tshwj xeeb ntawm kev tshuaj xyuas.
● Kev daws teeb meem siab:LC-MS muab siab- daws teeb meem loj, tso cai rau kev txiav txim siab ntawm prostaglandin pawg thiab cov qauv.
● Quantitative Accuracy:Los ntawm kev koom ua ke cov qauv sab hauv, LC-MS ua kom qhov tseeb thiab qhov tseeb ntawm prostaglandin quantification.
Tandem Mass Spectrometry (MS/MS lossis LC-MS/MS):
Tandem huab hwm coj spectrometry koom nrog kev siv cov khoom siv ntau yam ntsuas los muab cov ntaub ntawv ntxiv txog prostaglandins. Nws yog ib qho tseem ceeb heev rau:
● Structure Elucidation:MS / MS tuaj yeem tawg prostaglandin ions, muab cov ntaub ntawv hais txog lawv cov yam ntxwv, xws li txoj haujlwm ntawm ob daim ntawv cog lus thiab qhov xwm txheej ntawm cov saw hlau.
● Selective Detection:MS / MS tuaj yeem xaiv lub hom phiaj tshwj xeeb prostaglandin subtypes, txhim kho qhov tshwj xeeb ntawm kev tshuaj xyuas hauv cov qauv nyuaj.
Ntim thiab Shipping
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Ntim |
Peb muaj ntau qhov sib txawv ntawm cov iav thiab Foil hnab, koj tuaj yeem thov cov pob me me los yog ua tiav cov pob. |
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Kev xa khoom |
Thaum koj txiav txim tau muab tso rau, peb yuav ua nws sai li sai tau. Peb feem ntau xa cov pob los ntawm airfreight thiab pov hwm koj qhov kev yuav khoom tiv thaiv kev puas tsuaj thiab raug xa tawm raws sijhawm. |
Peb Cov Ntawv Pov Thawj
FAQ
Peb paub zoo-paub tias yog ib qho ntawm cov tib neeg prostaglandins manufacturers thiab lwm tus neeg nyob hauv Suav teb. Yog tias koj yuav mus yuav zoo tib neeg prostaglandins nrog tus nqi sib tw, txais tos kom tau txais cov ntaub ntawv ntau ntxiv los ntawm peb lub hoobkas. Tsis tas li, kev pabcuam customized muaj.