CAS Naj Npawb: 790299-79-5
Standard: Hauv tsev txheem
Masitinib, tseem hu ua Masitinib mesylate, yog kev tshawb fawb thiab kev loj hlob ntawm AB, kev kho mob rau ntau yam myeloma, platelet-derived growth factor alpha/beta receptor tyrosine kinase inhibitors hauv plab hnyuv stromal qog thiab prostate cancer.
Khoom Paub meej
|
Molecular Formula |
C28H30N6 OS |
|
Molar Mass |
498.64 |
|
Qhov ntom |
1.28 0± 0.06 g / cm3 (Tshaj tawm) |
|
Melting Point |
90-95 degree |
|
Solubility |
DMSO 00 mg/mL (200.54 mM); Dej<1 mg/mL (<1 mM);Ethanol 4 mg/mL (8.02 mM) |
|
pKa |
13.24 ± 0.70 (Tshaj tawm) |
|
Refractive Index |
1.682 |
|
Qhov tshwm sim |
Hwj chim |
|
Xim |
Off-White rau Pale Beige |
|
Kev cia khoom |
Lub tub yees |
Masitinib yog ib tug tswv cuab ntawm cov chav kawm ntawm Benzamides uas yog Carboxamide uas tshwm sim los ntawm cov ntaub ntawv condensation ntawm pawg carboxy. Nws yog ib qho kev xaiv ntawm qhov ncauj tyrosine kinase inhibitor. Nws muaj lub luag haujlwm ua tyrosine kinase inhibitor, tus neeg sawv cev antineoplastic thiab tshuaj tiv thaiv kab mob. Nws yog N-alkylpiperazine, ib tug tswv cuab ntawm 1, 3-thiazoles, ib tug tswv cuab ntawm pyridines thiab ib tug tswv cuab ntawm Benzamides.
Daim ntawv thov
Masitinib yog ib qho khoom siv tshuaj muaj zog uas tau pom tias muaj txiaj ntsig zoo hauv kev kho mob ntawm qee yam mob qog noj ntshav thiab kab mob inflammatory. Nws ua haujlwm los ntawm inhibiting cov haujlwm ntawm tyrosine kinases, uas yog cov enzymes koom nrog hauv kev loj hlob thiab kev loj hlob ntawm cov hlwb. Los ntawm kev thaiv cov haujlwm ntawm cov enzymes no, Masitinib tuaj yeem pab qeeb lossis nres kev loj hlob ntawm cov qog nqaij hlav cancer thiab txo qhov mob.
Masitinib yog siv los ua cov khoom xyaw tseem ceeb hauv cov tshuaj uas tau pom zoo rau kev kho mob ntawm cov kab mob plab hnyuv siab rau lub plab thiab cov kab mob mastocytosis hauv Europe. Nws tseem tab tom nrhiav kev sim tshuaj rau lwm yam kev siv, suav nrog kev kho mob ntawm amyotrophic lateral sclerosis (ALS), Alzheimer's disease, thiab ntau yam sclerosis.
Raws li cov khoom siv tshuaj nquag, Masitinib yuav tsum tau ua tib zoo tsim thiab tsim los xyuas kom meej nws purity, potency, thiab stability. Qhov no suav nrog cov txheej txheem tswj xyuas kom zoo thiab ua raws li kev coj ua zoo. Lwm cov khoom xyaw, xws li fillers thiab binders, kuj yuav raug ntxiv los tsim cov khoom siv tshuaj zaum kawg. Zuag qhia tag nrho, Masitinib sawv cev rau kev cog lus kho mob rau ntau yam kab mob thiab cov xwm txheej, thiab kev tshawb fawb tsis tu ncua yuav ua rau pom ntau dua ntawm nws cov txiaj ntsig thiab kev txwv.
Cov lus nug ntawm cov neeg siv khoom
Q: Koj lub Hoobkas nyob qhov twg?
A: Nws nyob hauv Torch Hi-tech Industrial Development Zone, Xiamen, Fujian, Suav.
Q: Thaum twg koj lub Hoobkas tsim?
A: Nws tau tsim nyob rau hauv 2013.
Q: Koj lub lag luam loj yog dab tsi?
A: Keeb kwm feem ntau xa mus rau Tebchaws Europe, South America, Middle East, thiab Asia, thiab tau txais kev qhuas thoob ntiaj teb los ntawm cov neeg siv khoom hauv zos thiab thoob ntiaj teb.
Cim npe nrov: Masitinib rau Veterinary CAS 790299-79-5, Tuam Tshoj masitinib rau Veterinary CAS 790299-79-5 manufacturers, lwm tus neeg, Hoobkas
