Neostigmine Methyl Sulfate yog siv dav siv tshuaj kho tsiaj cholinesterase inhibitor uas txhim khu kev ua haujlwm neuromuscular los ntawm kev tiv thaiv kev tawg ntawm acetylcholine, ib qho tseem ceeb neurotransmitter lub luag haujlwm rau cov leeg nqaij. Los ntawm kev nce qib acetylcholine ntawm cov hlab ntsha neuromuscular, nws txhim kho cov hlab ntsha - rau - cov leeg nqaij sib txuas lus thiab rov ua kom cov leeg muaj zog.
Cov txheej txheem no ua rau Neostigmine Methyl Sulfate yog ib qho tseem ceeb kho tus neeg saib xyuas hauv kev xyaum kho tsiaj rau cov leeg tsis muaj zog, neuromuscular mob, thiab tom qab- tshuaj loog rov qab.
Cov yam ntxwv ntawm lub cev & tshuaj lom neeg
| Feature | Kev piav qhia |
|---|---|
| Tshuaj npe | Neostigmine Methyl Sulfate |
| CAS Nr | 51-60-5 |
| Molecular Formula | C₁₃H₂₂N₂O₆S |
| Molecular Luj | 334.39 g / mol |
| Chemical Class | Cholinesterase inhibitor |
| Qhov tshwm sim | Dawb rau tawm -dawb crystalline hmoov |
| Solubility | Dawb soluble nyob rau hauv dej |
| pH (Kev daws teeb meem) | Feem ntau nruab nrab |
| Kev ruaj ntseg | Nyob ruaj khov nyob rau hauv kev pom zoo cia |
| Melting Point | ~ 150℃(decomposes) |
| Kev tsim qauv | Cov tshuaj txhaj tshuaj (IV, IM, SC) |
| Common Strengths | 0.5 mg / ml, 1 mg / ml |
| Cia | Tswj chav kub (20-25 ℃) |
| Ntim | ampoules los yog vials |
Mechanism ntawm Action
Neostigmine Methyl Sulfate inhibits acetylcholinesterase, enzyme uas degrades acetylcholine. Raws li qib acetylcholine nce:
- Neuromuscular teeb liab kis tau zoo
- Cov leeg nqaij ua kom muaj zog
- Tag nrho cov neuromuscular zog nce
Qhov kev txiav txim siab no ua rau nws muaj txiaj ntsig tshwj xeeb hauv cov teeb meem cuam tshuam rau kev sib tshuam neuromuscular.
Cov ntawv thov Veterinary tseem ceeb
1. Kev kho mob ntawm Myasthenia Gravis
Neostigmine Methyl Sulfate yog thawj zaug - kab kev kho mob rau myasthenia gravis, ib qho mob tshwm sim los ntawm cov hlab ntsha tsis zoo- kev sib txuas lus ntawm cov leeg.
Cov txiaj ntsig kho mob muaj xws li:
- Txhim kho cov leeg nqaij
- Txo kev qaug zog
- Txhim kho lub neej zoo
2. Kev tswj cov leeg tuag tes tuag taw thiab cov leeg tsis muaj zog
Cov tshuaj yog siv los kho cov kev txav mus los hauv cov tsiaj uas muaj:
- Ib ntus tuag tes tuag taw
- Limb qaug zog
- Cov leeg tsis ua haujlwm vim lub paj hlwb tsis ua haujlwm
Los ntawm kev txhim kho acetylcholine kev ua si, nws txhawb cov leeg nqaij, kev sib koom tes, thiab kev txav mus los.
3. Reversal of Anesthesia-Induced Muscle Relaxation
Hauv kev phais kws kho tsiaj, Neostigmine Methyl Sulfate feem ntau siv rau:
- Rov qab neuromuscular thaiv cov neeg ua haujlwm
- Ua kom nrawm tom qab- rov ua haujlwm rov qab
- Restore ib txwm ua pa thiab tswj cov leeg
Qhov no yog qhov tseem ceeb tshwj xeeb hauv cov tsiaj me thiab tsiaj txhu tom qab tshuaj loog.
4. Kev Siv Tshuaj Kho Mob hauv Neuromuscular Disorders
Cov kws kho tsiaj tuaj yeem siv Neostigmine Methyl Sulfate ua ib qho kev kuaj mob rau:
- Neuromuscular kis tsis tau
- Cov kab mob autoimmune neuromuscular
- Cov leeg tsis muaj zog
Cov lus teb zoo txhawb kev kuaj pom tseeb.
Kev nyab xeeb, ceev faj & Veterinary siv
Neostigmine Methyl Sulfate yog ib qho tshuaj muaj zog thiab yuav tsum tau ua raws li kws kho tsiaj saib xyuas.
Cov koob tshuaj muaj peev xwm -nyob ntawm cov kev mob tshwm sim muaj xws li:
- Tshaj salivation
- Cov leeg nqaij spasms
- Gastrointestinal cuam tshuam ( ntuav, raws plab)
- Bradycardia (lub plawv dhia qeeb)
Kev noj tshuaj kom zoo, saib xyuas, thiab ua raws li cov lus qhia kws kho tsiaj kom muaj kev nyab xeeb thiab muaj txiaj ntsig zoo.
Xaus
Neostigmine Methyl Sulfate (CAS 51-60-5) yog ib qho tshuaj ntau yam thiab tseem ceeb hauv cov kws kho tsiaj. Nws lub peev xwm los txhim kho kev ua haujlwm neuromuscular ua rau nws zoo rau:
- Myasthenia gravis
- Paralysis thiab cov leeg tsis muaj zog
- Tom qab- tshuaj loog rov qab
- Neuromuscular diagnostic ntsuam xyuas
Thaum siv kom raug, nws ua rau cov tsiaj muaj kev noj qab haus huv zoo, kev txav mus los, thiab tag nrho zoo - nyob thoob plaws ntau hom.
Cim npe nrov: api neostigmine methyl sulfate, Tuam Tshoj api neostigmine methyl sulfate manufacturers, lwm tus neeg, Hoobkas
