Tib neeg chorionic gonadotropin (HCG) yog ib yam tshuaj uas tsim los ntawm lub embryo thaum lub sij hawm cev xeeb tub thaum ntxov thiab ua lub luag haujlwm tseem ceeb hauv poj niam fertility. Nws pab fertility hauv cov hauv qab no:
1. Txhawb nqa luteal muaj nuj nqi
Ib lub luag haujlwm tseem ceeb ntawm HCG yog los txhawb kev ua haujlwm luteal. Lub corpus luteum yog cov ntaub so ntswg tsim los ntawm zes qe menyuam tom qab ovulation thiab yog lub luag haujlwm rau kev tso tawm ntawm progesterone (feem ntau yog progesterone). Progesterone yog qhov tseem ceeb rau kev tswj kom cev xeeb tub thaum ntxov vim nws ua rau lub cev tuab ntawm lub tsev menyuam thiab ua kom lub qe fertilized tuaj yeem ua tiav thiab muaj sia nyob hauv lub tsev menyuam. Yog tsis muaj progesterone txaus, lub qe fertilized yuav tsis ua tiav implant thiab ua rau nchuav menyuam. HCG xyuas kom meej tias qhov chaw nyob hauv lub tsev menyuam yog qhov tsim nyog rau kev saib xyuas ntawm cev xeeb tub los ntawm kev txhawb nqa lub cev luteum mus txuas ntxiv zais cov progesterone.
2. Txhawb kev txhim kho follicular thiab ovulation
Hauv kev pabcuam kev ua menyuam yaus (xws li hauv vitro fertilisation, IVF), HCG feem ntau yog siv los ua ovulation inducer. Thaum ib tug poj niam tab tom kho ovulation induction therapy, kev siv HCG ua raws li lub ncov ntuj ntawm luteinising hormone (LH), uas ua rau lub rupture ntawm ib tug paub tab follicle thiab tso tawm ntawm lub qe. Cov txheej txheem no tseem ceeb heev rau kev xeeb tub, tshwj xeeb tshaj yog tias tus poj niam muaj kev ua haujlwm tsis zoo ntawm zes qe menyuam lossis mob ovulation. HCG yog siv los txhim kho ovulation kev vam meej.
3. Txhim kho lub embryo
HCG tseem yog ib qho tseem ceeb ntawm kev tswj hwm ntawm embryo txoj kev loj hlob. Thaum cev xeeb tub thaum ntxov, HCG pab tswj kev tso tawm ntawm progesterone kom txog thaum lub cev xeeb tub thiab muaj peev xwm tsim tau cov tshuaj hormones txaus los txhawb kev xeeb tub. Cov txheej txheem no yog qhov tseem ceeb rau kev loj hlob ntawm embryonic.
4. Kev siv tshuaj kho mob
Clinically, HCG txhaj tshuaj kuj tseem siv tau los pab cov poj niam cev xeeb tub tau txais kev kho mob xws li hauv vitro fertilization thiab insemination. Los ntawm exogenous supplementation ntawm HCG, lub sij hawm ntawm ovulation yuav ua tau ntau precisely tswj, ua rau kom muaj feem ntawm conception. Tsis tas li ntawd, HCG yog siv los kuaj rau cov theem thaum ntxov ntawm cev xeeb tub, vim tias HCG concentrations nce sai heev nyob rau hauv thaum ntxov cev xeeb tub, uas ua rau nws yog lub hauv paus rau feem ntau siv cev xeeb tub kuaj strips los kuaj cev xeeb tub.
Zuag qhia tag nrho, lub luag haujlwm ntawm HCG hauv kev pab cov poj niam muaj kev xeeb tub yog ib qho tseem ceeb heev, tsis tsuas yog nws ua lub luag haujlwm tseem ceeb hauv kev pabcuam kev yug me nyuam xws li hauv vitro fertilisation, tab sis nws tseem tswj hwm txoj kev loj hlob ntawm embryo, txhawb kev ua haujlwm corpus luteum thiab ua kom cov khoom tsim tawm ib txwm muaj. progesterone thaum cev xeeb tub.