Khoom Taw Qhia
CAS Naj Npawb: 1192491-61-4
Standard: Hauv tsev txheem
Avibactam sodium yog ib qho uas tsis yog - -lactam -lactamase inhibitor siv nrog ceftazidime los kho cov kab mob hauv plab thiab cov kab mob urinary nyuaj uas tshwm sim los ntawm ntau cov tshuaj tiv thaiv kab mob gram-negative kab mob.
Daim ntawv thov
Avibactam sodium, uas tsis yog - -lactam -lactamase inhibitor, muaj ntau yam kev siv hauv kev tawm tsam ntau yam tshuaj tiv thaiv kab mob gram-tsis zoo.
Avibactam sodium muaj cov ntawv thov tseem ceeb hauv qab no:
1. Restoring cov tshuaj tiv thaiv kab mob ntawm tus khub cephalosporins tiv thaiv ntau cov tshuaj tiv thaiv kab mob gram-negative kab mob hauv vitro[5]
2. Kho cov kab mob sib kis hauv plab ua ke nrog metronidazole
3. Kho cov kab mob urinary nyuaj, suav nrog pyelonephritis, tshwm sim los ntawm cov kab mob tiv thaiv kab mob.
4. Inhibiting ntau chav kawm ntawm -lactamases, nrog rau chav kawm A (KPCs, CTX-M, TEM, SHV), chav kawm C (AmpC), thiab qee chav kawm D serine -lactamases, los tawm tsam cov tshuaj tiv thaiv kab mob.
5. Muaj peev xwm rau qhov ncauj bioavailability los ntawm prodrug analogues nrog sulfate esters thiab carboxylate esters, uas tuaj yeem cleaved nyob rau hauv me me kom tso unesterified avibactam
Avibactam sodium yog ib qho kev txhim kho tseem ceeb hauv kev kho cov kab mob uas tshwm sim los ntawm ntau cov tshuaj tiv thaiv kab mob gram-tsis zoo, vim nws tuaj yeem rov ua kom muaj txiaj ntsig ntawm tus khub tshuaj tua kab mob thiab inhibit ntau yam -lactamases.
Cim npe nrov: Antimicrobial avibactam sodium, Tuam Tshoj antimicrobial avibactam sodium manufacturers, lwm tus neeg, Hoobkas
